Thelansis
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Leptomeningeal metastases (LM) is a severe condition in which cancer spreads to the membranes lining the brain and spinal cord. It is most caused by breast, lung, or melanoma cancer. The symptoms of LM are caused by cancer cells clogging the normal exits for cerebrospinal fluid (CSF), causing a fluid buildup and increased pressure in the brain. This increased pressure can cause vague but uncomfortable symptoms, such as headaches, nausea, vision changes, and difficulty walking. Cancer cells can also disturb nerves exiting the brain, causing numbness, weakness, or pain. LM is a difficult condition to treat, and there is no cure. However, treatment can help to reduce the symptoms and prolong survival. Treatment typically involves a combination of chemotherapy, radiation therapy, and steroids. The goal of treatment is to reduce pressure on the brain and reduce the number of cancer cells causing the pressure. The prognosis for patients with LM remains poor.โฆ